Both the new Q5 and Grand Cherokee have child safety locks to prevent children from opening the rear doors. The new Q5 has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The Grand Cherokee’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
The new Q5 has a standard front seat center airbag, which deploys between the driver and front passenger, protecting them from injuries caused by striking each other in serious side impacts. The Grand Cherokee doesn’t offer front seat center airbags.
The new Q5 has standard Secondary Collision Brake Assist, which automatically apply the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The Grand Cherokee doesn’t offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.
To provide maximum traction and stability on all roads, All-Wheel Drive is standard on the new Q5. But it costs extra on the Grand Cherokee.
Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The new Q5 has Car-to-X Services, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The Grand Cherokee doesn’t offer a system that can receive automated systems from infrastructure.
Both the new Q5 and Grand Cherokee have rear cross-traffic warning, but the new Q5 has Rear Cross-Traffic Assist (automatically applies the brakes) to better prevent a collision when backing near traffic. The Grand Cherokee’s Rear Cross Path Detection doesn’t automatically brake.
Both the new Q5 and the Grand Cherokee have standard driver and passenger frontal airbags, front side-impact airbags, side-impact head airbags, front seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning and available around view monitors.

